Homeless Pothead To Health CEO (EP 91)
I brought Len May back to talk about how he went from “pothead kid the cops kicked out” to building a DNA platform that helps doctors actually tailor meds, hormones, and health plans to real people instead of imaginary averages. We talk ADHD as a superpower, antidepressants that spark suicidal thoughts, exosomes that helped him avoid knee surgery, and why your food, friends, and flow state matter just as much as your prescriptions.
This part of the conversation dives into the messy, human side of health — not just lab reports and buzzwords. Len explains why he avoided pharmaceuticals after watching his grandfather suffer through stroke after stroke while his family juggled bags of meds and side effects. That early distrust pushed him toward cannabis as his own medicine for ADHD, which later evolved into deep work in genetics, epigenetics, and the endocannabinoid system. Today, his EndoDNA platform lets doctors swab patients, pull blood work, and use an AI called BIOS to generate treatment plans that include pharmaceuticals, supplements, and lifestyle changes tailored to that specific person.
We cover hormone testing for women dealing with early perimenopause and rough menopause, men quietly going through andropause, and how personalized dosing can change everything from pellets to GLP‑1 drugs. Len shares how their clinical trials are exploring personalized approaches for conditions like Alzheimer’s, Parkinson’s, and autism, and why the real magic is the feedback loop: epigenetic data, bloodwork, and outcomes feeding the AI so treatment gets more and more individualized. We also zoom back out to regular life: the junk we call food, how fake “healthy” processed stuff speeds up aging, why movement and resistance training matter as we get older, and how cutting loose the “energy vampires” in your life might be as important as changing your diet.
Chapters
- 00:19 Introduction to Len May
- 01:09 Traditional Medicine and Personal Choices
- 03:29 Women’s Hormone Health Insights
- 05:33 Expanding into Male Hormone Health
- 06:37 The Role of Pharmaceuticals in Personalized Medicine
- 09:42 Exciting Discoveries in Precision Medicine
- 13:28 The Shift in Traditional Medical Practices
- 15:34 Patient Empowerment and Healthcare Choices
- 18:29 Accessing Personal Health Platforms
- 19:39 The FDA and Health Innovation
- 23:27 The Impact of Medication Choices
- 27:01 Common Health Mistakes and Solutions
- 33:36 The Importance of Community and Environment
- 36:39 Coaching and Personal Development
- 40:32 Embracing Individuality and Curiosity
- 41:27 Conclusion and Takeaways
Guests: Len May, EndoDNA
- Website: https://endodna.com
- Website: https://lenmaycoaching.com
- LinkedIn: https://www.linkedin.com/in/lenmay
Companies / Vendors / Products Mentioned
- U.S. Food and Drug Administration (FDA): https://www.fda.gov/
- 23andMe: https://www.23andme.com
- Epidiolex: https://www.epidiolex.com
- Ozempic (semaglutide): https://www.ozempic.com
- 23andMe: https://www.23andme.com
- Jack of All Trades, Master of Sum: ADHD and Polymath, Rewiring the Modern Genius: https://amzn.to/48fGTuV
=== MUSIC LICENSE CERTIFICATE: Envato Elements Item
- Item Title: Healthy Eating
- Item URL: https://elements.envato.com/healthy-eating-VNN4M4P
- Author Username: CrazyTunes
- Licensee: Marvin Bee
- Registered Project Name: Unhealthy Podcast
- License Date: January 3rd, 2026
- Item License Code: XPFS6HD54W
=== About the Unhealthy Podcast
Hosted by Marvin Bee (Uncle Marv), the Unhealthy Podcast dives into real conversations about health, wellness, and everyday habits that impact how we live, work, and age. From nutrition myths to stress management and tech-life balance, Uncle Marv brings humor, insight, and honesty to every episode.
- Visit our website: https://www.unhealthypodcast.com/
- Connect on Facebook: https://www.facebook.com/iamunclemarv
- Connect on LinkedIn: https://www.linkedin.com/in/marvinbee/
Follow and Subscribe: Stay updated with new episodes every week on Apple Podcasts, Spotify, YouTube, and more. Join the conversation about real-life health, fitness, and personal growth from the lens of an everyday guy striving to be healthier.
Len May is a polymath, global speaker, and recognized authority in personalized medicine, genetics, and human optimization. As CEO and Co-Founder of EndoDNA, he’s pioneering a new era of precision health, using genomics and AI to help people understand how their unique biology shapes their wellness, focus, and fulfillment.
Over the last 25 years, Len has built and exited multiple multi-million-dollar ventures while leading EndoDNA’s breakthrough work in genetic wellness and personalized medicine.
The company’s patented DNA→Protocol platform now powers personalized protocols across hormone health, longevity, cognition, and nutrition, serving thousands of patients and practitioners worldwide.
His upcoming book, Jack of All Trades and Master of Some, explores how ADD, curiosity, and diverse talents can become superpowers for mastery and meaning.
As host of the popular podcast Everything Is Personal, Len brings these conversations to life, interviewing leading thinkers in science, wellness, and culture.
